Mp36-01 an analysis of the psychological bother in men with peyronie's disease

You have accessJournal of UrologyCME1 Apr 2023MP36-01 AN ANALYSIS OF THE PSYCHOLOGICAL BOTHER IN MEN WITH PEYRONIE'S DISEASE Luis F. Novaes, Lawrence C. Jenkins, Jean E. Terrier, Hisanori Taniguchi, Bruno Nascimento, Sigrid Carlsson, Christian Nelson, Jose M. Flores, and John P. Mulhall Luis F. NovaesLuis F. Novaes More articles by this author , Lawrence C. JenkinsLawrence C. Jenkins More articles by this author , Jean E. TerrierJean E. Terrier More articles by this author , Hisanori TaniguchiHisanori Taniguchi More articles by this author , Bruno NascimentoBruno Nascimento More articles by this author , Sigrid CarlssonSigrid Carlsson More articles by this author , Christian NelsonChristian Nelson More articles by this author , Jose M. FloresJose M. Flores More articles by this author , and John P. MulhallJohn P. Mulhall More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003270.01AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: There is an association between Peyronie's disease (PD) and psychological bother, depression and relationship dissatisfaction. We aimed to describe the prevalence of these psychosocial issues using validated instruments. METHODS: On presentation, all patients with PD who responded to 3 validated questionnaires were included in this study. The inventories included: the Peyronie’s Disease Questionnaire (PDQ), the Center for Epidemiologic Studies Depression Scale (CES-D), and the Self-Esteem and Relationship (SEAR) questionnaire. The PDQ has 3 subdomains, psychological and physical symptoms, penile pain, and bother signs. With worsening negative impact, PDQ scores are higher; a bother domain score ≥9 indicates clinically meaningful bother. A CES-D score, ≥16/60 suggests clinical depression. The SEAR contains 14 questions, divided into the domains of sexual relationship and confidence (self-esteem; overall relationship), with a normalized score of 0-100, (higher scores better QOL). Demographics and PD characteristics are reported. We evaluated potential predictors of psychological bother. Parameters included in univariable (UVA) and multivariable (MVA) analysis models: age, sexual orientation, PD duration, multiplanar curvature, pain, intercourse, curvature, penile instability. RESULTS: 720 patients were analyzed. Median age 58 [52, 64] years, 20% had ≥2 comorbidities, 7% were current smokers. Median PD duration was 10 [4, 24] months, 28% multiplanar curvature, median degree of the primary was 32° [21, 46]. Curvature location: mid-shaft 64%, distal 25%, proximal 11%. 49% had dorsal, 37% lateral, and 14% ventral curvature. Median PDQ scores: psychological and physical (0-24) was 9 [4, 14]; pain (0-30) was 3 [0, 8]; bother (0-16) was 4 [3, 6]; 5% had clinically significant bother. Median CES-D scores 8 [3, 15], 23% had scores ≥16, indicating clinical depression. Median SEAR scores: sexual relationship 28 [16, 41]; confidence 32 [23, 41]. On UVA, pain (OR: 4.67; 95% CI: 1.4, 14.8; p: 0.009) curvature magnitude (OR: 1.47; 95% CI: 1.1, 1.9; p: 0.007) were predictors of bother. Median PDQ pain scores in bothered patients was 14.5 [8.5, 21.2], vs 2 [0, 7] in non-bothered. On MVA (Table 1), pain was the only predictor of bother. CONCLUSIONS: Pain and curvature is associated with bother, and 1 in 4 PD patients have clinical depression. Source of Funding: SMSNA © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e479 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Luis F. Novaes More articles by this author Lawrence C. Jenkins More articles by this author Jean E. Terrier More articles by this author Hisanori Taniguchi More articles by this author Bruno Nascimento More articles by this author Sigrid Carlsson More articles by this author Christian Nelson More articles by this author Jose M. Flores More articles by this author John P. Mulhall More articles by this author Expand All Advertisement PDF downloadLoading ...