Digital image analysis for biothreat detection via rapid centrifugal microfluidic orthogonal flow immunocapture

M. Shane Woolf,Leah M. Dignan,Scott M. Karas,Hannah M. Lewis,Sabrina N. Kim,Geoffrey M. Geise,Haley L. DeMers,Derrick Hau,Marcellene A. Gates-Hollingsworth,David P. AuCoin,James P. Landers

Analytical Methods（2023）

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摘要

We report centrifugally-driven, orthogonal flow immunocapture (cOFI) of Zaire Ebola virus-like particles with an accompanying rich, colorimetric image analysis approach that does not require commercial ‘strip readers’ or custom analysis algorithms.

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