Biosynthesis of Zirconium dioxide nanoparticles by Streptomyces sp. HC1: Characterization and Bioactivity Zirkonyum dioksit nanopartikülllerinin Streptomyces sp. HC1 tarafından biyosentezi: Karakterizasyon ve Biyoaktivite

Nanoparticles can be synthesized in many different ways. However, synthesis methods that are except of biosynthesis are very expensive and environmentally hazardous processes. Nanoparticles with various morphologies and shapes are frequently used in biosynthesis studies due to the advantages of their small size. Bio-synthesized nanoparticles gain great importance for reasons such as prevention of environmental pollution and being economical. Zirconium dioxide nanoparticles(ZrO2 NPs) are prominent especially in dental coatings and photocatalytic applications. With this study, for the first time, zirconium dioxide nanoparticles biologically synthesized with Streptomyces sp. HC1 strain were produced. The bio-synthesized ZrO2 NPs were characterized different methods and instruments. Then the nanoparticles were studied their bioactivity especially antimicrobial and antibiofilm.The results confirmed the efficient antimicrobial effect of zirkonium dioxide nanoparticles as well as efficient antibiofilm effect. The synthesis of ZrO2 nanoparticles from Streptomyces sp. HC1 by biological synthesis and determination of the bioactivity of these nanoparticles were reported for the first time in this work.