Supplementary Data from <i>ERINA</i> Is an Estrogen-Responsive LncRNA That Drives Breast Cancer through the E2F1/RB1 Pathway

Supplementary Figures 1-5. Supplementary Figure 1. ERINA is a nuclear lncRNA that affects the survival and cell proliferation marker of ER-positive breast cancer patients. Supplementary Figure 2. ERINA knockdown and overexpression efficiency and the morphology change of knockdown cells. Supplementary Figure 3. RNA sequencing analysis showed the number of up-regulated genes and downregulated genes in T47D cells. Supplementary Figure 4. GSEA analysis revealed ERINA played a crucial role in RB1-involved pathway. Supplementary Figure 5. ChIP-seq analysis reveals the binding of RNA polymerase II within the promoter region of ERINA. (A) Alignment of RNA polymerase II ChIP-seq in MCF7 cells. The binding peak and genomic locus are shown.