Supplementary Figures S1-S6 from Enhanced Survival with Implantable Scaffolds That Capture Metastatic Breast Cancer Cells <i>In Vivo</i>

Micro-porous PCL scaffolds persist and maintain a space for extended times in vivo (S1); Host response following implantation of micro-porous PCL scaffolds in the dorsal subcutaneous space of an NSG mouse in vivo (S2); Dynamics of immune cell populations in the spleen of BALB/c mice with a PCL scaffold implant at day 0, 5, 10, and 15 post tumor inoculation (S3); Micro-porous PCL scaffolds enable recruitment of human MDA-MD-231BR cells in a chronic model of scaffold implantation (S4); Micro-porous PCL scaffolds do not significantly improve survival in a post-surgical model of breast cancer metastasis with day 6 post tumor inoculation resection (S5); Anti-Gr-1 depletion significantly reduces the presence of CD11b+Gr-1hiLy6C- MDSCs in the spleen primary tumor and scaffold (S6).