Supplementary Methods, Figures, Tables, References from Inhibiting Translation Elongation with SVC112 Suppresses Cancer Stem Cells and Inhibits Growth in Head and Neck Squamous Carcinoma

SF1 is related to Fig. 1 and Fig. 2. SVC112 inhibits tumor cells growth and enhances the effects of radiation. SF2 is related to Fig. 3. SVC112 combined with radiation inhibits growth of HNSCC PDX tumors. SF3. Ribo-seq analysis of HNSCC cells treated with SVC112. SF4 is related to Fig. 5. SVC112 suppresses proteins related to proliferation and CSCs. SF5 is related to Fig. 5. Reversibility of SVC112 treatment effects. SF6 is related to Fig. 5. Analysis of SVC112 resistance. SF7 is related to Fig. 6. Effects of exogenous Sox2 expression of SVC112 treatment. ST1 is related to Fig 1. Radiation dose modifying effects by SVC112. ST2 is related to Fig 3. Characteristics of HNSCC PDX cases treated with radiation and SVC112. ST3 is related to Fig 3. Incidence of histopathology in SVC112 treated mice. ST4. Ribo-seq analysis (GSEA, Hallmark Pathways) of HNSCC cells treated with SVC112.