Supplementary Information from Heterochromatin Protein 1α Mediates Development and Aggressiveness of Neuroendocrine Prostate Cancer

Supplementary materials and methods used in this study. Supplementary table with primer sequences. Figure S1, Histological feature of PDX models and heatmaps of PDX and clinical cohorts. Figure S2, IHC staining of HP1α in PDX models, and expression of Hp1α mRNA in NPp53 CRPC GEM models. Figure S3, Additional analyses of HP1α function in NEPC cells. Figure S4, Additional analyses of HP1α function in NE transdifferentiation. Figure S5, Additional analyses of the repressive function of HP1α on AR and REST expression. Figure S6, Additional analyses of the function of HP1α. Supplementary references.