Supplementary Figure 4 from A Novel Tankyrase Inhibitor Decreases Canonical Wnt Signaling in Colon Carcinoma Cells and Reduces Tumor Growth in Conditional APC Mutant Mice

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PDF file - 171K, Superposition of JW55 (docking) and IWR-1 (X-ray, PDB code 3UA9) in the PARP domain of TNKS2 show similar binding characteristics.

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