Supplementary Figures 1 - 5 from Sequential Gene Targeting to Make Chimeric Tumor Models with <i>De Novo</i> Chromosomal Abnormalities

PDF file - 2135K, Fig. S1 Targeting vectors for Mll-ENl fast throughput translocator analysis. Fig. S2 The LMO2-Cre knock in targeting vector. Fig. S3 Comparison of leukaemia incidence rate in the triple targeted chimaeric mice and germline-transmission translocator mice. Fig. S4 Sequence of the genomic PCR product after FLP-mediated deletion. Fig. S5 Analysis of mRNA levels in chimaera-derived tumour cells.