Figure S2 Inhibition of mTORC1 and glutamate cysteine ligase induces cytotoxicity in Tsc2-/- MEFs from mTORC1-Driven Tumor Cells Are Highly Sensitive to Therapeutic Targeting by Antagonists of Oxidative Stress

Cell viability of Tsc2-/- MEFs and WT MEFs treated with single agent and combination; siRNA-mediated knockdown of GCLC with or without rapamycin; cell viability of ELT3-V3 cells. Cell death study of ELT3-V3 vs. ELT3-T3 and 621-102 vs. 621-103