Supplementary Information from Attenuated TRAF3 Fosters Activation of Alternative NF-κB and Reduced Expression of Antiviral Interferon, TP53, and RB to Promote HPV-Positive Head and Neck Cancers

crossref(2023)

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摘要

Supplementary Methods, related references, and Figures: S1, 2 Effects TRAF3 on alternate pathway proteins; S2, Effects TRAF3 on alternate pathway proteins; S3, Effects of TNF/LTB on NF-kB reporter activity and TRAF3 siRNA on alternate pathway; S4, Effects TRAF3 on cisplatin and anti-apoptotic genes; S5, TRAF3 loss with passage; S6-8, TRAF3 effects on IRF expression; S9, TRAF3 effects on TP53, RB, p21; S10, TRAF3 effects on E6; S11, Diagram illustrating the genetic and cellular mechanisms linked to deficient TRAF3 in HPV+ HNSCC.

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