Supplementary Material from Androgen Receptor-Independent Function of FoxA1 in Prostate Cancer Metastasis

Supplementary Material - PDF file 1368K, Figure S1. FoxA1 promotes cell cycle progress ion but inhibits cell motility. Figure S2. FoxA1 promotes cell pro liferation through the AR. Figure S3. FoxA1 inhibits PC-3M cell inva sion independently of the AR. Figure S4. WB analysis of Vimentin in FoxA1 knockdown LNCaP cells. Figure S5. FoxA1 directly suppresses SLUG expression. Figure S6. FoxA1 expression is up-regulated in localized PCa, but is significantly down- regulated in metastatic PCa. Figure S7. FoxA1 mutants fail to bind the SLUG enhancer. Table S1. GO analysis of genes repressed by shFoxA1 (i .e. FoxA1-induced genes) in LNCaP cells. Table S2. GO analysis of genes induced by shFoxA1 (i.e. FoxA1-repressed) in LNCaP cells. Table S3. GO analysis of genes repressed by siFoxA1 (i .e. FoxA1-induced genes) in LNCaP cells. Table S4. GO analysis of genes induced by siFoxA1 (i .e. FoxA1-repressed) in LNCaP cells. Table S5. GO analysis of genes repressed by shFoxA1 (i .e. FoxA1-induced genes) in 22RV1 cells. Table S6. GO analysis of genes induced by shFoxA1 (i.e. FoxA1-repressed) 22RV1 cells. Table S7. Sequences of oligonucleotid es used in this study