Supplementary Methods, Tables 1-2, Figures 1-4 from Hedgehog Signaling Is a Novel Therapeutic Target in Tamoxifen-Resistant Breast Cancer Aberrantly Activated by PI3K/AKT Pathway

PDF file - 596K, Table S1: Predicted GSK3b phosphorylation sites on SMO. TableS2: Predicted GSK3b phosphorylation sites on SMO. FIG S1: Generation of cell lines resistant to increasing concentration of tamoxifen. FIG S2: Mammosphere formation assay with cells resistant to increasing concentration of tamoxifen. FIG S3: Effect of Gli1 depletion on OHTR and T47D cells. FIG S4: Regulation of GLI1 by PI3k/Akt pathway.