Supplementary Figures 1-10 from CXCR2 Expression in Tumor Cells Is a Poor Prognostic Factor and Promotes Invasion and Metastasis in Lung Adenocarcinoma

PDF file - 581K, Supplementary Figure 1: Distribution of cytoplasmic CXCR2 protein expression in 262 non-small cell lung cancer cell lines. Supplementary Figure 2: CXCR2 expression in tumor cells according to EGFR and KRAS mutation status. Supplementary Figure 3: Kaplan-Meier curves Supplementary Figure 4: Distribution of expression of CXCR2 and its ligand genes Supplementary Figure 5: CXCR2/CXCR2 ligands cluster is associated with a worse overall survival in patients with lung adenocarcinoma (N=442) Supplementary Figure 6: TTF-1 gene expression was more frequently lower in lung adenocarcinomas Supplementary Figure 7: The first two principal components were computed using expression of CXCR2 and its ligand genes Supplementary Figure 8: The first two principal components were computed using expression of CXCR2 and its ligand genes Supplementary Figure 9: Expression of (A) CXCL1, (B) CXCL2, (C) CXCL3, and (D) CXCL6 genes was negatively correlated with the level of their promoter methylation as indicated by average beta-value. Supplementary Figure 10: The effect of two doses of decitabine