Supplementary figures 1-7 from Full-Length Semaphorin-3C Is an Inhibitor of Tumor Lymphangiogenesis and Metastasis

Supplementary figures 1-7. Contains the 7 supplementary figures (1S to 7S) in PDF format. Fig. 1S: Characterization of the expression of class-3 semaphorin receptors in LEC Fig. 2S: Semaphorins that fail to contract LEC nevertheless induce contraction of other cell types. Fig. 3S: Measurement of cell contraction using the xCELLigence dual plate (RTCA) machine and FR-sema3C induced changes in in thentent of M2 macrophages in the tumors. Fig. 4S: Inhibition of BrdU incorporation in lEC by FR-sema3C. Fig. 5S: The effect of FR-sema3C on the Distribution of intrtumoral and peritumoral lymphatics Fig. 6S: The effect of tumor size on the development of lymph node metastases. Fig. 7: P65-Sema3C promotes the survival of A549 lung cancer cells.