Supplementary Figures S1-S9 from Hybrid Manganese Dioxide Nanoparticles Potentiate Radiation Therapy by Modulating Tumor Hypoxia

Characterization of NPs (S1); Immunofluorescence detection and quantification of EMT6 tumor hypoxia (S2); IF detection and quantification of EMT6 tumor hypoxia (S3); Quantification of IHC images (S4); Effect of IT treatment with MDNPs alone or combined with RT on murine and human breast tumors growth (S5); Effect of IT administered MDNPs alone or in combination with RT on the growth of murine EMT6 breast tumor (S6); Effect of IV treatment with MDNPs alone or combined with RT on murine and human breast tumors growth (S7); H&E stained mammary fat pad tissues of a healthy mouse and a LMD+RT surviving mouse (S8); Effect of MDNPs treatment post irradiation (S9).