Supplementary Figures S1-S10 from Cellular Factors Promoting Resistance to Effective Treatment of Glioma with Oncolytic Myxoma Virus

Immunophenotyping of the K1492 glioma microenvironment in response to sterile injury (S1); Immunophenotyping of the K1492 glioma microenvironment after Myxoma virus treatment (S2); Virus infected areas of K1492 tumours are accompanied by polymorphonuclear cell infiltration (S3); K1861 and Spontaneous NPcis gliomas in C57Bl/6 mice have significant microglia and/or GIM recruitment (S4); Non-tumour bearing CCR2-deficient animals are only slightly impaired in clearing MYXV (S5); CCR2-deficient mice have an exaggerated recruitment of NK and T cells to the K1492 glioma in response to Myxoma treatment (S6); Minocycline administration mimics CCR2-null viral clearance kinetics but does not result in a survival advantage (S7); K1492 tumours in IL2Rγ mice are significantly depleted of NK and T cell populations (S8); Non-tumour bearing IL2Rγ-deficient animals are impaired in clearing MYXV (S9); Single low-dose cyclophosphamide combined with Myxoma treatment did result in improved treatment efficacy or viral infection (S10).