Supplementary Figures 1 - 4 from Characterization of Torin2, an ATP-Competitive Inhibitor of mTOR, ATM, and ATR

Qingsong Liu,Chunxiao Xu,Sivapriya Kirubakaran,Xin Zhang, Wooyoung Hur,Yan Liu, Nicholas P. Kwiatkowski,Jinhua Wang,Kenneth D. Westover,Peng Gao,Dalia Ercan,Mario Niepel,Carson C. Thoreen,Seong A. Kang,Matthew P. Patricelli,Yuchuan Wang,Tanya Tupper,Abigail Altabef,Hidemasa Kawamura, Kathryn D. Held,Danny M. Chou, Stephen J. Elledge,Pasi A. Janne,Kwok-Kin Wong,David M. Sabatini,Nathanael S. Gray

crossref（2023）

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摘要

PDF file - 719K, Supplemental figure 1. Torin2 on PC-3 wide type cell line, the IB was made after 30 min treatment of drug at indicated concentrations. Supplemental figure 2. Torin1, Torin2, AZD8055 and BEZ235 on HeLa and HCT-116 cell line at different time point with a dose responsive drug treatment. Supplemental figure 3. PET-CT experiment of short term treatment of drugs. Supplemental figure 4. PDG-PET determination of drug treatment response with statistics

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