Supplemental Figure 4 from Genomic Profiling of Pediatric Acute Myeloid Leukemia Reveals a Changing Mutational Landscape from Disease Diagnosis to Relapse

Jason E. Farrar, Heather L. Schuback,Rhonda E. Ries,Daniel Wai,Oliver A. Hampton,Lisa R. Trevino,Todd A. Alonzo,Jaime M. Guidry Auvil,Tanja M. Davidsen,Patee Gesuwan,Leandro Hermida,Donna M. Muzny,Ninad Dewal,Navin Rustagi,Lora R. Lewis,Alan S. Gamis,David A. Wheeler,Malcolm A. Smith,Daniela S. Gerhard,Soheil Meshinchi

crossref（2023）

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摘要

Clonal cluster analysis. Mutations were clustered using DBSCAN based on the VAF and graphed according to timepoint. Panels A-T illustrate possible scenarios of how individual mutations may originate, evolve, and resolve based on VAF.

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