Estrogen ameliorates sepsis-induced vascular hyporeactivity in thoracic aorta of female rats via permissive effect of GRα expression

Shan Wang,Jue Wu,Kai Yang,Chunlei Liu,Xin Li,Liben Wu,Xiaoqin Qi,Ruizhi Zhang,Wenfeng Ni,Jinlian Pei,Fangyan Gu, Bing Lu,Yan Wang,Yaping Tian

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS（2023）

引用 1|浏览9

暂无评分

摘要

•Estrogen upregulated GRα expression in VSMCs during sepsis.•Estrogen promoted glucocorticoids permissive effect in the vessels.•Estrogen reversed the vascular hyporeactivity due to sepsis.•Estrogen improved vascular injury via modulating GRα expression during sepsis.

查看译文

关键词

Sepsis, Vascular dysfunction, Estrogen, Glucocorticoid

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要