Single-Molecule Measurement of Carbonic Anhydrase in Cation Coordinated Environment Using MspA Nanopore+

Dandan Song,Yunjiao Wang,Shaoxia Zhang,Lingyu Zhao,Linyu Gong,Liyuan Liang,Liang Wang

CHINESE JOURNAL OF CHEMISTRY（2023）

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摘要

Background and Originality Content Carbonic anhydrase(CA)is an attractive protein model for bi-ocatalysis,biophysics and beyond.Different from most other proteins,carbonic anhydrase is in abundant presence in wide living system,such as mammalian tissues,botany,algae,and bacteria.

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关键词

C arbonic anhydrase,Nanopore biosensing,Biocatalytic biophysical analysis,Cation coordinated environment,Renal tumor biomarker,Protein model,Ionic channel

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