Case of osteopetrosis with multiple impacted primary and permanent teeth diagnosed at eight years old

Background: Osteopetrosis is a rare skeletal disease characterized by increased bone density caused by a malfunction of osteoclasts. Case presentation: An 8-year-4-month-old girl with multiple primary and permanent tooth impaction was diagnosed with osteopetrosis. In spite of typical manifestations of osteo-petrosis in early childhood, including visual and hearing impairments, short stature, and dental abnormalities, diagnosis was severely delayed. Conclusion: Multiple impacted teeth may indicate a possible diagnosis of osteopetrosis. Dentists should perform an orthopantomography examination when eruption distur-bances are encountered and systemic disease should also be suspected, with referral to a pediatrician when necessary.(c) 2023 Japanese Society of Pediatric Dentistry. Published by Elsevier Ltd. All rights reserved.