Epileptic Spasms in CDKL5 Deficiency Disorder: Delayed Treatment and Poor Response to First-line Therapies.

Heather E Olson,Scott Demarest,Elia Pestana-Knight,Ahsan N Moosa,Xiaoming Zhang, José R Pérez-Pérez, Judy Weisenberg, Erin O'Connor Prange,Eric D Marsh,Rajsekar R Rajaraman,Bernhard Suter,Akshat Katyayan,Isabel Haviland,Carolyn Daniels,Bo Zhang,Caitlin Greene,Michelle DeLeo,Lindsay Swanson,Jamie Love-Nichols,Timothy Benke,Chellamani Harini,Annapurna Poduri

Epilepsia（2023）

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摘要

Compared to the broad group of infants with ES, children with ES in the setting of CDD often experience longer lead time to treatment and respond poorly to standard treatments. Development of alternative treatments for ES in CDD is needed.

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关键词

CDD,National Infantile Spasms Consortium,adrenocorticotropic hormone,hypsarrhythmia,prednisolone,vigabatrin

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