Membrane and Soluble CD137 in Systemic Lupus Erythematosus: Role as Biomarkers for Disease Activity.

Fulvia Ceccarelli,Francesco Natalucci,Alessandra Di Filippo,Giulio Olivieri,Chiara Napoletano,Aurelia Rughetti,Marianna Nuti,Ilaria Grazia Zizzari,Fabrizio Conti

Journal of immunology research（2023）

引用 0|浏览29

暂无评分

摘要

Our results suggest a possible involvement of CD137-CD137L axis in SLE pathogenesis, as demonstrated by higher expression of CD137 on CD4+ cells in SLE compared with HS. Furthermore, the positive correlation between SLEDAI-2K and membrane CD137 expression on CD4+ cells, as well as soluble CD137, indicates a possible use as biomarkers for disease activity.

查看译文

关键词

soluble cd137,systemic lupus erythematosus,lupus erythematosus,biomarkers

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要