Seven New Lobane Diterpenoids from the Soft Coral Lobophytum catalai .

Seven new lobane diterpenoids, namely, lobocatalens A-G (-), were isolated from the Xisha soft coral . Their structures, including their absolute configurations, were elucidated via spectroscopic analysis, comparison with the literature data, QM-MNR, and TDDFT-ECD calculations. Among them, lobocatalen A () is a new lobane diterpenoid with an unusual ether linkage between C-14 and C-18. In addition, compound showed moderate anti-inflammatory activity in the zebrafish models and cytotoxic activity against the K562 human cancer cell line.