Effect of SLCO1B1 c.521T>C polymorphism on the lipid response to statins in people living with HIV on a boosted protease inhibitor containing regimen.

Catia Marzolini,Matthias Cavassini,Dominique L Braun,Anna Hachfeld,Enos Bernasconi,Alexandra Calmy,Patrick Schmid,Manuel Battegay,Luigia Elzi

British journal of clinical pharmacology（2023）

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摘要

The lipid lowering effect of statins tended to be attenuated by SLCO1B1 polymorphism and progressively declined as total cholesterol under the boosted protease inhibitor treatment decreased.

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关键词

SLCO1B1,lipid lowering response,polymorphism,protease inhibitor,statin

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