Extracting Cognitive Behavioral Features from Iterated Rock-Scissors-Paper Played Against An Artificial-Intelligence Agent

Quantification of human behavior in a social context may lead to discovery of subtle behavioral variations in a population that can be used to improve classification and screening for psychiatric disorders, and provide more accurate targeting in the development of interventions and biomedical treatments. However, it is difficult to study social interaction in a controlled, reproducible environment, as well as analyze the resulting behavior. In this research, we describe an experimental framework that utilizes a game of iterated Rock-Scissors-Paper played against an artificial intelligence agent, and a behavioral hypothesis of rule-switching to motivate analytical methods, that will extract behavioral features with potential clinical relevance from game data. ### Competing Interest Statement The authors have declared no competing interest. ### Funding Statement This study did not receive any funding. ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: Institutional Review Board of Worcester Polytechnic Institute gave ethical approval for this work. I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable. Yes All data produced in the present study are available upon reasonable request to the authors