Aerobic Coupling of Organophosphonium Salts with Alkenes: Catalyst‐Free C(sp3)‐C(sp2) Bond Formation

An aerobic coupling of benzhydryl phosphonium salts with simple alkenes for accessing trisubstituted olefins is developed under metal-free, catalyst-free, and additive-free conditions. New C(sp(3))-C(sp(2)) bond is constructed via the C-P and C-H bond functionalization by synergistically using O-2 as a "green" oxidant and DMSO as a promoter. The method also distinguishes itself by its broad substrate scope and synthetic potential. Particularly, the use of 1,3,5-trimethoxybenzene fragment in the resulting products as a carbon-based leaving group for further transformations is proved to be feasible.