Investigation of the effects of mir-219-1 gene variants on the development of disease in non-small cell lung cancer patients.

Sevgi Kalkanli Tas,Ender Coskunpinar,Pinar Yildiz,Mesut Bayraktaroğlu,Tuba Kose,Derya Altunkanat,Duygu Kirkik,Mustafa Tukenmez

African health sciences（2022）

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摘要

miRNA single nucleotide polymorphisms can be used as genetic biomarkers to predict cancer susceptibility, early diagnosis, and prognosis. Our study has shown that two variants of miR-219-1 were not related to NSCLC in the Turkish population. The reason for this can be differences in ethnicity, regions, and background of population and these differences could lead to various outcomes.

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关键词

NSCLC,miR-219-1 gene,single-nucleotide polymorphisms

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