Chronic alcohol administration alters metabolomic profile of murine bone marrow.

Tássia Tatiane Pontes Pereira,Filipe Fideles Duarte-Andrade,Jéssica Gardone Vitório, Taiane do Espírito Santo Pereira,Flavia Rayssa Braga Martins,Jéssica Amanda Marques Souza,Nathália Luisa Malacco,Eliza Mathias Melo, Carolina Raíssa Costa Picossi,Ernani Pinto,Ricardo Santiago Gomez,Mauro Martins Teixeira,Adriana Nori de Macedo,Gisele André Baptista Canuto,Frederico Marianetti Soriani

Frontiers in immunology（2023）

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摘要

Our results demonstrate for the first time in the literature the effects of alcohol consumption on the metabolome content of hematopoietic tissue and open a wide range of further studies to investigate mechanisms by which alcohol compromises the cellular function of the immune system.

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关键词

alcoholism,bone marrow,cell function,immune system,metabolites,metabolome

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