Successful Treatment of Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Patients With Immunodeficiency With Extended Nirmatrelvir/Ritonavir: Case Series.

Madison Breeden,Samuel L Aitken,Ji Hoon Baang,Misty Gravelin,Daniel R Kaul,Adam S Lauring,Lindsay A Petty,Kevin S Gregg

Open forum infectious diseases（2023）

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摘要

Immunocompromised patients with B-cell deficiencies are at risk for prolonged symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We describe 4 patients treated for B-cell malignancies with B-cell-depleting therapies who developed persistent SARS-CoV-2 infection and had resolution of symptoms following an extended course of nirmatrelvir/ritonavir.

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关键词

SARS-CoV-2,immunodeficiency,prolonged infection

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