Characterization of trophoblast mitochondrial function and responses to testosterone treatment in ACH-3P cells.

Agata M Parsons, Ranjitha Raja Rajendran,Luke A Whitcomb,Gerrit J Bouma,Adam J Chicco

Placenta（2023）

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摘要

These studies establish ACH-3P as a suitable cell line for investigating trophoblast mitochondrial function, and provide foundational evidence supporting links between hyperandrogenism and placental mitochondrial ROS production with potential relevance to several common pregnancy disorders.

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关键词

ACH-3P,Androgens,BeWo,Mitochondria,Oxidative stress,Placenta

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