Role of lipidomic signatures in prognostication of breast cancer - A pilot study

Introduction: Lipid reprogramming has a major attribution to rewiring of the oncogenic signalling pathways during onset and progression of cancer as well as establishing crosstalk between cancer cells and tumour microenvironment. Therefore, sphingolipids can provide breast cancer (BC) subtype- and stage-specific signatures/biomarkers that can help in prognosis, and prediction of the treatment outcome for subtypes like TNBC and luminal.