Age-related changes in plasma biomarkers and their association with mortality in COVID-19.

Erik H A Michels,Brent Appelman,Justin de Brabander,Rombout B E van Amstel,Osoul Chouchane,Christine C A van Linge,Alex R Schuurman,Tom D Y Reijnders, Titia A L Sulzer,Augustijn M Klarenbeek,Renée A Douma,Lieuwe D J Bos,W Joost Wiersinga,Hessel Peters-Sengers,Tom van der Poll

The European respiratory journal（2023）

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摘要

Ageing is associated with a strong and broad modification of the host response to COVID-19, and specific immune changes likely contribute to increased mortality in older patients. These results may provide insight into potential age-specific immunomodulatory targets in COVID-19.

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关键词

plasma biomarkers,mortality,age-related

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