Glycoprotein V exerts local control of fibrin
Nature Cardiovascular Research(2023)
摘要
Preserving hemostasis while preventing pathological thrombosis has been a central goal in drug development. A new way to restore hemostasis is suggested by the finding that glycoprotein V is cleaved by thrombin on activated platelets, negatively regulating clotting at sites of vascular injury.
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关键词
Coagulation system,Platelets,Thrombosis,Cardiovascular Biology
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