Virtual Screening and Biological Evaluation of Novel Low Molecular Weight Protein Tyrosine Phosphatase Inhibitor for the Treatment of Insulin Resistance

Bo Feng, Xu Dong,Zhen Liu, Jie Zhang, Hongyu Liu,Yuan Xu

Drug Design, Development and Therapy(2023)

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摘要
In summary, this study presents a versatile virtual screening pipeline for potential LMPTP inhibitor discovery and provides a novel-scaffold lead compound that is worthy of further modification to get more potent LMPTP inhibitors.
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关键词
LMPTP inhibitor,insulin resistance,low molecular weight protein tyrosine phosphatase,molecular docking,virtual screening
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