Brigatinib-associated autoimmune hepatitis: A case report.

Mahmut Buyuksimsek,Ali Ogul,Abdullah Evren Yetisir,Berna Bozkurt Duman,Mert Tohumcuoglu,Timucin Cil,Tolga Koseci,Mehmet Mutlu Kidi,Hilmi Erdem Sumbul

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners（2023）

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摘要

Increased creatine kinase and lipase levels are common side effects associated with brigatinib, while liver toxicity is rare. Autoimmune hepatitis due to brigatinib was considered because of hepatic toxicity that developed in the fifth month of treatment and responded well to steroids.

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ALK,Autoimmune hepatitis,ROS1,brigatinib

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