Proteomic Analysis of Complement Proteins in Glomerular Diseases.

Sanjeev Sethi,Lilian Monteiro P Palma,Jason D Theis,Fernando C Fervenza

Kidney international reports（2023）

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摘要

This study shows accumulation of specific complement proteins in GN. The complement pathways, complement proteins, and the amount of complement protein deposition are variable in different types of GN. Selective targeting of complement pathways may be a novel option in the treatment of GN.

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关键词

complement,glomerulonephritis,kidney,laser microdissection,mass spectrometry

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