Candidate biomarkers as predictors of future kidney disease and cardiovascular dysfunction in adolescents with type 2 diabetes.

Fida Bacha,Laure El Ghormli,Barbara H Braffett,Amy S Shah,Santica M Marcovina,Lorraine E Levitt Katz,Steven M Willi,Sonia Caprio,Ruban Dhaliwal,Samuel S Gidding

Diabetes research and clinical practice（2023）

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摘要

Circulating biomarkers of endothelial dysfunction and markers of β-cell dysfunction and insulin sensitivity could be used in a more personalized risk assessment of kidney disease in youth-onset type 2 diabetes. However, biomarkers studied have limited value in predicting cardiac dysfunction or vascular stiffness.

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关键词

Cardiovascular disease,Circulating biomarkers,Kidney disease,Pediatrics,Risk assessment,Type 2 diabetes

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