Metagenomic Deep Sequencing for Orbital Inflammatory Disease.

M Reza Vagefi,Oluwatobi O Idowu,Amanda Miller,Thuy Doan,Cindi Chen,Armin Hinterwirth,Lina Zhong,Meleha Ahmad,Davin C Ashraf,Seanna R Grob,Robert C Kersten,Bryan J Winn

Ocular immunology and inflammation（2023）

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摘要

A unique transcriptome signature was found when comparing idiopathic dacryoadenitis to IgG4-RD. This suggests that MDS can identify differentially expressed genes in OID. Such insight could potentially provide a better understanding of host gene expression and the inflammatory pathways involved in OID.

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关键词

Dacryoadenitis,IgG4-related disease,metagenomic deep sequencing,orbital inflammatory disease,transcriptomics

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