Sub-50 nm Core–Shell Nanoparticles with pH-Responsive Squeezing Release Effect for Targeting Therapy of Hepatocellular Carcinoma

Jian-Bo Qu,Huan-Jie Che, Bo Gao,Gang-Feng Li,Xue-Fei Zhang,Yi-Bo Zhang,Xiaojuan Wang

Journal of Materials Chemistry B（2023）

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摘要

Drug delivery system with high drug loading capacity, low leakage at physiological pH, and rapid release at the lesion site remains an ongoing challenge. In this work, core-shell poly(6-O-methacryloyl-D-galactose)@poly(tertbutyl methacrylate)...

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关键词

core–shell nanoparticles,hepatocellular carcinoma,targeting therapy,ph-responsive

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