LPCAT1 levels in the placenta, the maternal plasma and the fetal plasma do not predict fetal lung responses to glucocorticoids in a sheep model of pregnancy

Tsukasa Takahashi,Erin L. Fee,Yuki Takahashi,Haruo Usuda,Sean W.D. Carter,Hideyuki Ikeda,Masatoshi Saito,Yusaku Kumagai,James P. Bridges,Alan H. Jobe,Mahesh A. Choolani,Matthew W. Kemp

Placenta（2023）

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摘要

LPCAT1 expression in the fetal lung was associated with the durability of glucocorticoid effects on fetal lung maturation. However, LPCAT1 expression in the placenta, the fetal plasma, and the maternal plasma was neither associated with, nor predictive of fetal lung maturation after glucocorticoid treatment in a sheep model of pregnancy.

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关键词

fetal lung responses,glucocorticoids,fetal plasma,maternal plasma,placenta

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