Multi-Polymorphism Analysis Reveals Joint Effects in Males With Chronic Central Serous Chorioretinopathy.

Zhen Ji Chen,Danny S C Ng,Ling-Ping Cen,Tsz Kin Ng,Mary Ho,Marten E Brelen,Tai-Ping Li,Shi Yao Lu,Pancy O S Tam,Alvin L Young,Weiqi Chen,Jason C Yam,Haoyu Chen,Clement C Tham,Chi Pui Pang,Li Jia Chen

Investigative ophthalmology & visual science（2023）

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摘要

This study revealed main and joint effects of SNPs in CFH and TNFRSF10A on cCSCR, and suggested CFH as a potential genetic factor underlying the male predilection of cCSCR. Further replication in other study populations is needed.

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关键词

genetic association, central serous chorioretinopathy, complement factor H, CFH, TNFRSF10A

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