Impact of Concomitant Prostate Cancer Medications on Efficacy and Safety of Relugolix Versus Leuprolide in Men With Advanced Prostate Cancer.

Daniel J George,Fred Saad,Michael S Cookson,Daniel R Saltzstein,Ronald Tutrone,Alberto Bossi,Bruce Brown,Bryan Selby,Sophia Lu,David Buckley,Bertrand Tombal,Neal D Shore

Clinical genitourinary cancer（2023）

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摘要

Treatment with relugolix was associated with similar efficacy and safety profiles with and without concomitant enzalutamide or docetaxel. Standard-of-care use of relugolix in combination with these agents is supported by these data.

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关键词

Androgen deprivation therapy,Concomitant therapy,Pharmacokinetic/pharmacodynamic analyses

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