Extended platelet transfusion in bleeding patients with platelet transfusion refractoriness.

Platelet transfusion refractoriness (PTR), defined as the failure to increase platelet number after transfusion [ [1] Stanworth S.J. Navarrete C. Estcourt L. Marsh J. Platelet refractoriness – practical approaches and ongoing dilemmas in patient management. Br J Haematol. 2015; 171: 297-305https://doi.org/10.1111/bjh.13597 Crossref PubMed Scopus (155) Google Scholar ], is a common finding among patients with haematological conditions undergoing chemotherapy [ [2] Comont T. Tavitian S. Bardiaux L. Fort M. Debiol B. Morère D. et al. Platelet transfusion refractoriness in patients with acute myeloid leukemia treated by intensive chemotherapy. Leuk Res. 2017; 61: 62-67https://doi.org/10.1016/j.leukres.2017.08.015 Crossref PubMed Scopus (24) Google Scholar ], who consequently may develop life-threatening bleeding complications.