Extensive coronary artery calcification is associated with all-cause mortality patients with a history of cancer.

Recent studies have shown a steady increase in the prevalence of cardiovascular disease among patients with cancer, 1 Agarwal M.A. Aggarwal A. Rastogi S. Ventura H.O. Lavie C.J. Cardiovascular disease burden in cancer patients from 2003 to 2014. Eur Heart J Qual Outcomes. 2017; 4: 69-70 Crossref Scopus (13) Google Scholar with cardiovascular mortality overtaking cancer mortality in many cancer types. 2 Strongman H. Gadd S. Matthews A.A. et al. Does cardiovascular mortality overtake cancer mortality during cancer survivorship?: an English retrospective cohort study. JACC CardioOncol. 2022; 4: 113-123 Crossref Scopus (13) Google Scholar Coronary artery calcium (CAC) is a robust predictor of future cardiovascular risk and increasing CAC category is associated with an increased risk of all-cause mortality. 3 Tota-Maharaj R. Joshi P.H. Budoff M.J. et al. Usefulness of regional distribution of coronary artery calcium to improve the prediction of all-cause mortality. Am J Cardiol. 2015; 115: 1229-1234 Abstract Full Text Full Text PDF PubMed Scopus (43) Google Scholar We performed a retrospective analysis to determine the risk associated with CAC in patients with a history of cancer compared to patients without a history of cancer.