TIMP3 induces gene expression partly through PI3K and their association with vascularization and heart rate.

Zi-Meng Xia,Meng-Yu Song,Yan-Ling Chen,Guozhen Cui,Dong Fan

Frontiers in cardiovascular medicine（2023）

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摘要

TIMP3 can regulate expression of multiple genes partly through PI3K. Some DEGs were associated with activation of vascularization and some with heart rate reduction. This study suggests that TIMP3 can potentially modulate cardiovascular functions DEGs.

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关键词

angiogenesis,cardiovascular system,gene expression,heart rate,phosphoinositide-3-Kinase (PI3K),signal pathway,tissue inhibitor of metalloproteinase 3

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