Insights into the inhibitory activity and mechanism of action of flavonoids from the stems and branches of Acer mono Maxim. against α-glucosidase via kinetic analysis, molecular docking, and molecular dynamics simulations

•12 Flavonoids were isolated from the stems and branches of A. mono Maxim.•Two dimeric flavan-3-ols (1 and 2) showed strong inhibitory effect on α-glucosidase.•Compounds 1 and 2 inhibited α-glucosidase in a non-competitive model.•Molecular docking and dynamics revealed the binding interactions of active compounds.