AGK (Acylglycerol Kinase) Potentiates Arterial Thrombosis by Affecting Talin-1 and αIIbβ3-Mediated Bidirectional Signaling Pathway.

Peng Zhang,Haojie Jiang,Mina Yang,Changlong Bi,Kandi Zhang,Dongsheng Liu,Meng Wei,Zheyi Jiang,Keyu Lv,Chao Fang,Junling Liu,Tiantian Zhang,Yanyan Xu,Junfeng Zhang

Arteriosclerosis, thrombosis, and vascular biology（2023）

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摘要

AGK, through its kinase activity, potentiates platelet activation and arterial thrombosis by promoting Talin-1 Ser425 phosphorylation and affecting the αIIbβ3-mediated bidirectional signaling pathway.

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关键词

acylglycerol kinase,fibrinogen,lysophosphatidic acid,talin-1,thrombosis

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