High-speed compressive wide-field fluorescence microscopy with an alternant deep denoisers-based image reconstruction algorithm

Yilin He,Yunhua Yao,Yu He,Zhengqi Huang,Pengpeng Ding,Dalong Qi,Zhiyong Wang,Tianqing Jia,Zhenrong Sun,Shian Zhang

Optics and Lasers in Engineering（2023）

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摘要

•Compressive wide-field fluorescence microscopy was developed to break through the speed limit of the camera.•An iterative algorithm with alternant deep denoisers was proposed to greatly improve the image reconstruction quality.•Compressive wide-field fluorescence microscopy was successfully utilized to observe the high-speed hydrodynamics.

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关键词

Wide-field fluorescence microscopy,High-speed microscopy,Compressive imaging,Image reconstruction,Deep denoisers

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